Neurostimulation in the treatment of refractory and super-refractory status epilepticus

This article is part of the Special Issue “Proceedings of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures”.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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Conditions:   Absence Epilepsy;   Ketogenic Dieting;   Epilepsy, Absence Interventions:   Other: Modified Atkins Diet;   Drug: Absence epilepsy medications Sponsor:   Johns Hopkins University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We report a case of inaugural tonic-clonic generalized seizure while refueli...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Some epileptic spasms are classified into focal-onset seizures. However, the cortical network underlying this kind of spasm seizure is not yet clear. Four patients with epileptic spasms who underwent intracranial electrode implantation and focal resection surgery were studied. All the patients had good outcomes, and three of them with intellectual disability showed improved intelligence after surgery. The power spectra characteristics of electrocorticography and the dynamic functional network changes of epileptic spasms were investigated. Electrocorticography power in the resected zone peaked 0.5 seconds before the clinica...
Source: NeuroReport - Category: Neurology Tags: Integrative Systems Source Type: research
In 2011, a homozygous mutation in GOSR2 (c.430G  > T; p. Gly144Trp) was reported as a novel cause of Progressive Myoclonus Epilepsy (PME) with early-onset ataxia. Interestingly, the ancestors of patients originate from countries bound to the North Sea, hence the condition was termed North Sea PME (NSPME). Until now, only 20 patients have been rep orted in literature. Here, we provide a detailed description of clinical and neurophysiological data of seventeen patients.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research
In this study, spontaneous, recurrent seizures were established in a mouse model of pilocarpine-induced status epilepticus. After post-status epilepticus stabilization, baseline behavioral seizures were monitored for 30 d.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research
Conclusion: Post-herpetic anti-NMDAr AIE could arise several months after infection. Clinicians must be aware of this possibility, particularly if cognitive and/or psychiatric symptoms occurred after a remitting period. In our two cases, only rituximab was associated with clinical improvement.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Compumedics secures approval for neuroimaging system for epilepsy and pre-surgical brain function mapping.
Source: Diagnostic Imaging - Category: Radiology Authors: Tags: New Products Source Type: news
In Reply We thank Singh et al for their comments on our article demonstrating the benefits of specialist neurology and comprehensive epilepsy care on mortality in patients with epilepsy. We agree that evidence-based care should be driven by data. In a global environment of accelerating health care costs, the same methods should be used to demonstrate value for money. However, it may be unsurprising that bespoke care improves outcomes; particularly pertinent for countries offering universal health coverage, the unequivocal demonstration of benefit is an indispensable prerequisite for advocates of the judicious use of finite...
Source: JAMA Neurology - Category: Neurology Source Type: research
To the Editor Gaps in epilepsy are far more pervasive than the frequently mentioned treatment gap. The data gap is the most pervasive. We just do not know enough. The less we know, the more unconcerned we remain, and the less our efforts, including allocating resources, the more we inadvertently extend the status quo. Data from regions with the least substantial epilepsy care and the highest premature mortality attributable to epilepsy are not available. Data that do emerge are often incomplete and disadvantaged by concerns of less than strict compliance with the rigors of scientific methods. Excess premature mortality has...
Source: JAMA Neurology - Category: Neurology Source Type: research
The malformations of cortical development (most FCD) were the most common pathological type for children cases in China with drug ‐resistant seizures. It was speculated further that the FCD patients with shorter duration of epilepsy before surgery seem to have a higher ratio of being seizure‐free after surgery. AbstractObjectivesThe drug ‐resistant seizures are characterized by frequent and severe onset of seizures in childhood. There is only little literature had extensively explored the types of pathological brain damage in Chinese children cases. The present study aims to investigate the histopathologic findings a...
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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