Cerebral Small Vessel Disease Burden and All-Cause Mortality: Mayo Clinic Florida Familial Cerebrovascular Diseases Registry

Goal: Cerebral small vessel disease (CSVD) leads to cognitive decline, gait disturbances, mood changes, and an increased risk of stroke. The goal of this study is to describe the relationship between a composite radiographic CSVD score and all-cause mortality. Materials and Methods: Data were collected from a prospective registry of patients with and without cerebrovascular disease from November 2010 through April 2018. The radiographic Total CSVD Score (tSVD) ranges from 0 (minimal disease) to 4 (severe disease), based on detection of lacunar infarcts, cerebral microbleeds, perivascular spaces, and subcortical or periventricular white matter hyperintensities.

Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2019 Category: Neurology Authors: Eric D. Goldstein, Mohammed K. Badi, Tasneem F. Hasan, Elizabeth R. Lesser, David O. Hodge, Michelle P. Lin, James F. Meschia Source Type: research