The change of PD1, PDL1 in experimental autoimmune encephalomyelitis treated by 1,25(OH)2D3

In this study, we employed 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) to induce tolerogenic dendritic cells (VD3-DCs) revealing their therapeutic effect through an increase in the development of the negative regulatory signaling pathway programmed death 1 (PD1)/programmed death ligand 1 (PDL1).

https://www.jni-journal.com/article/S0165-5728(19)30418-7/fulltext?rss=yes

Source: Journal of Neuroimmunology - October 31, 2019 Category: Allergy & Immunology Authors: Qingqing Cao, Chao Zheng, Zhongxiang Xie, Lingling Liu, Jie Zhu, Tao Jin Tags: Short communication Source Type: research