Longitudinally Measured Fibrinolysis Factors are Strong Predictors of Clinical Outcome in Patients with Chronic Heart Failure: The Bio-SHiFT Study.

CONCLUSION:  Longitudinally measured PAI-1, uPA, and suPAR are strongly associated with adverse cardiac events during the course of CHF. If future research confirms our results, these fibrinolytic factors may carry potential for improved, and personalized, heart failure surveillance and treatment monitoring.
PMID: 31659734 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - October 27, 2019 Category: Hematology Authors: van den Berg VJ, Bouwens E, Umans VAWM, de Maat M, Manintveld OC, Caliskan K, Constantinescu AA, Mouthaan H, Cornel JH, Baart S, Akkerhuis KM, Boersma E, Kardys I Tags: Thromb Haemost Source Type: research