Metformin plus first-line chemotherapy versus chemotherapy alone in the treatment of epithelial ovarian cancer: a prospective open-label pilot trial

ConclusionsWithin the limitations of the small sample size, there was no evidence of meaningful effect on PFS by metformin even though evidence of modulation of IGF-1 signaling axis was apparent.

Source: Cancer Chemotherapy and Pharmacology - October 30, 2019 Category: Cancer & Oncology Source Type: research