Methylphenidate and Continuous Spike and Wave During Sleep in a Child With Attention Deficit Hyperactivity Disorder

This article presents the case of a young girl with attention-deficit/hyperactivity disorder and behavioral problems on Depakote (valproic acid) who had an abnormal EEG with left centroparietal spikes but no history of electrographic seizures. She experienced a convulsion the day after her first dose of methylphenidate, and repeat EEG demonstrated continuous spike and slow wave during sleep. This case report suggests that children with continuous spike and slow wave during sleep may have a higher risk of developing seizures with methylphenidate treatment.

Source: Pediatric Neurology - July 1, 2013 Category: Neurology Authors: Volney L. Sheen, Maithreyi Shankar, Isaac Marin-Valencia, Carolyn H. Bridgemohan, Alcy R. Torres Tags: Clinical Observations Source Type: research