Can tailored nanoceria act as a prebiotic? Report on improved lipid profile and gut microbiota in obese mice
ConclusionDietary application of nanoceria combined with probiotic strainsL. casei IMV B-7280,B. animalis VKB, andB. animals VKL has significantly reduced both free and bound cholesterol levels in serum. Simultaneous administration of probiotics and cerium nanoparticles as a prebiotic, in various combinations, significantly enhanced positive individual effects of them on the gut microbiota spectrum. The presented results provide novel insights into mechanisms behind nutritional supplements and open new perspectives for application of probiotics combined with substances demonstrating prebiotic qualities benefiting, therefore, the host health. Follow-up translational measures are discussed to bring new knowledge from lab to the patient. If validated in a large-scale clinical study, this approach might be instrumental for primary and secondary prevention in obese individual and patients diagnosed with diabetes. To this end, individualized prediction and treatments tailored to the person are strongly recommended to benefit the health condition of affected individuals.
Bayer to significantly step-up its sustainability efforts2030 target to be carbon neutral in own operations / Ambitious 2030 objectives for access to health and nutrition in low- and middle-income countries and underserved communities / Measurable sustainability targets to be incorporated into management compensationmehr ...
HOW TO get rid of visceral fat: Visceral fat ’s positioning in the body means carrying an excess amount of it could have potentially deadly consequences. Diet can drastically reduce or increase the build-up of visceral fat and evidence makes a strong case for cutting down on a certain culprit.