You 're Not an Engineer, You 're a Creative Problem Solver

If you ever go to work for Kablooe Design, you'll quickly learn you are no longer an engineer or a product designer. "When you come on board here you've got a new title, and your title is, 'person who solves problems in creative ways and makes them become a reality. That's your title now'," said Tom Kramer, president and CEO at Kablooe Design, a Coon Rapids, MN-based firm. Kramer participated in a point/counterpoint discussion at MD&M Minneapolis about the challenges of finding the right balance between design and functionality in product development. To help make his point, Kramer told the following engineering joke: A doctor, a rabbi, and an engineer went golfing together. They kept having to wait on a group in front of them who were going through the course considerably slower. Finally, the doctor asked one of the golf course staff members what the deal was with the group in front of them going so slow and not letting them play through. The staff member explained that the slower group was part of a blind golfing association and all the golfers in the group were blind. The doctor said he had some friends who specialize in optical surgery and he wondered if his buddies might be able to help the blind golfers in some way. The rabbi was moved by the boldness of the blind golfers and said he would pray for them. The engineer, on the other hand, looks at the guy and asks, "why don't you just have them golf at night?" Kramer...
Source: MDDI - Category: Medical Devices Authors: Tags: MD & M Minneapolis Design R Source Type: news

Related Links:

Publication date: Available online 14 December 2019Source: Biosensors and BioelectronicsAuthor(s): A. Ben Tahar, K. Żelechowska, J.F. Biernat, E. Paluszkiewicz, P. Cinquin, D. Martin, A. ZebdaAbstractThe direct electrical connection of laccase on the electrode surface is a key feature in the design of efficient and stable biocathodes. However, laccase can perform a direct electron transfer only when it is in the preferred orientation toward the electrode. Here we report the investigation of the orientation of laccase from white rot fungus on multi-walled carbon nanotube surface modified with a naphthalene group. Naphthyla...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
This article presents a unique 3D biocompatible Aluminum-based quantum structure (QS) for in vitro cancer detection using Surface Enhanced Raman Scattering (SERS). The Al-based QSs fabricated using ultrashort pulsed laser are of two distinct surface characters, wrinkled and smooth spherical. The limit of detection for chemical sensing of Crystal Violet and Rhodamine 6G by the Al-QS was driven up to single molecule sensing (femtomolar concentration). Biological sensing of cysteine, a disease biomarker and carcinoembryonic antigen (CEA), a cancer biomarker was also tested by the Al-QS. The ability of in vitro cell detection ...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 14 December 2019Source: Biotechnology ReportsAuthor(s): Seema Mehandia, S.C. Sharma, Shailendra Kumar AryaAbstractA laccase producing new bacterial strain (Alcaligenes faecalis XF1) was isolated from green site of Chandigarh (India) by standard screening method. Nutrient broth medium containing 0.2 mM CuSO4 was used for the production of laccase. Maximum production (110 U/ml) was achieved after four days of incubation. The extracellular laccase from the medium was purified by simple salt precipitation and ion exchange technique to get 3.8 fold purified protein with 1637.8 U/mg spec...
Source: Biotechnology Reports - Category: Biotechnology Source Type: research
This study suggests that these bioformulations could be essential towards sustainable agricultural science deprived of harming the ecosystem. The synthesized bioformulations have enormous potential to be commercially explored for agriculture use.Graphical abstract
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 15 December 2019Source: Molecular Phylogenetics and EvolutionAuthor(s): Elena V. Romanova, Yurij S. Bukin, Kirill V. Mikhailov, Maria D. Logacheva, Vladimir V. Aleoshin, Dmitry Yu. SherbakovAbstractThe evolution of tRNA genes in mitochondrial (mt) genomes is a complex process that includes duplications, degenerations, and transpositions, as well as a specific process of identity change through mutations in the anticodon (tRNA gene remolding or tRNA gene recruitment). Using amphipod-specific tRNA models for annotation, we show that tRNA duplications are more common in the mt genomes of amp...
Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
In this study, we reported the synthesis, characterization and activity-structure relationship of novel β-amino carbonyl compounds. Some novel bis-β-amino carbonyl (4a-e) and mono-β-amino carbonyl (5a-e) compounds were synthesized by using CeCl3·7H2O catalyzed Mannich-type reaction. The title compounds were characterized by FTIR, elemental analysis, 13C NMR and 1H NMR techniques. In addition, the crystal and molecular structures of 5a, 5d and 5e were illuminated by single crystal X-ray diffraction. The activity-structure relationship was established by analyzing the enzyme activity of synthesized &bet...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
In this study, four different weight% of Punica granatum fruit peel extract were used as green stabilizers to synthesize IONPs followed by a series of characterization experiments and in vitro anticancer evaluation. Results revealed that all synthesized IONPs have high degree of crystallinity and purity. The optimum saturation magnetization, and hydrodynamic size were found to be ∼69 emu.g−1, and 26.52 nm, respectively. Morphological studies demonstrated that adding peel extract decreased size of NPs with the average particle size below 11 nm. Cytotoxicity assay showed that the IONPs were not react...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: 15 March 2020Source: Journal of Molecular Structure, Volume 1204Author(s): Yu-Ling Li, Li-Ping Zheng, Hui Nie, Yu-Fei Wang, Jian-Hua Yao, Jia Li, Jing-Jing Li, Xiao-Li Zhou, Huan-Feng Wang, Hai-Yan WangAbstractOne new Zn(Ⅱ) metal–organic framework, [Zn3(tib)2(BPT)2]·7H2O (ZZIT-1) [ZZIT-1 = Zhengzhou Institute of technology, tib = 1,3,5-tris(1-imidazolyl)benzene, H3BPT = biphenyl-3,4′,5-tricarboxylic acid], has been synthesized and characterized. ZZIT-1 is a two-fold interpenetrating 3D framework structure. The gas/vapor adsorption behavior and luminescenc...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: 15 March 2020Source: Journal of Molecular Structure, Volume 1204Author(s): Manish Paul, Gayatree Panda, Pradeep Kumar Das Mohapatra, Hrudayanath ThatoiAbstractComparative sequence alignment, molecular modeling and docking analyses were performed taking 5 microbial (3 bacteria and 2 fungi) cellulase enzymes and its substrate β-D glucose in order to understand the enzyme-substrate interaction and binding affinity associated with cellulose hydrolysis. Amino acids such as Val114, Ala255, Val288, Val289, and Ser301 of Streptomyces sp. Endoglucanase-1 shown to bind with β-D glucose. The binding energy...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: 15 March 2020Source: Journal of Molecular Structure, Volume 1204Author(s): A.D. Herrera-España, J. Us-Martín, S. Hernández-Ortega, G. Mirón-López, L. Quijano, J.R. Villanueva-Toledo, G.J. Mena-RejónAbstractThe structural modification of natural products has shown to be a remarkable tool in the generation of novel bioactive molecules. Herein, the synthesis, structural analysis and anticancer activity of the novel triterpenoid thiazole 3 is reported. The synthesis was carried out through the bromination of ochraceolide A (1) and the subsequent heterocyclic condensat...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
More News: Brain | Eyes | Learning | Medical Devices | Neurology | Neurosurgery | Training | Universities & Medical Training