Antiarrhythmic effects of renal sympathetic denervation in patients with refractory ventricular arrhythmias and structural heart disease

The demonstrated effectiveness of implantable cardioverter-defibrillators (ICDs) for primary and secondary preventions of sudden cardiac death has resulted in an increasing number of patients presenting with recurrent, appropriate ICD shocks for ventricular tachycardia (VT).1 In a selected group of patients with VT such as those included in the study by Bradfield et  al2 in this issue of HeartRhythm, autonomic modulation is considered as an adjunctive treatment option after failed catheter-based VT ablation and antiarrhythmic drug therapy.
Source: Heart Rhythm - Category: Cardiology Authors: Tags: Editorial Commentary Source Type: research

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Conclusion: Video-assisted CSD should be considered as a treatment option for patients with potentially dangerous arrhythmias that do not respond to conventional treatment, especially in recurrent ventricular tachycardia. PMID: 31588139 [PubMed - in process]
Source: Archivos de Cardiologia de Mexico - Category: Cardiology Authors: Tags: Arch Cardiol Mex Source Type: research
The demonstrated effectiveness of implantable cardioverter-defibrillators (ICDs) for primary and secondary preventions of sudden cardiac death has resulted in an increasing number of patients presenting with recurrent, appropriate ICD shocks for ventricular tachycardia VT.(1) In a selected group of VT patients such as those included in the study by Bradfield and colleagues (2) in this issue of Heart Rhythm, autonomic modulation is considered as adjunctive treatment option after failed catheter-based VT ablation and anti-arrhythmic drug therapy.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
ConclusionSGB increased cSNRT without changing heart rate. CSD was more beneficial for patients with mild ‐to‐moderate heart failure and faster VA.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ CLINICAL Source Type: research
Left cardiac sympathetic denervation (LCSD) is as an effective treatment for long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, and in select cases of substrate-mediated ventricular tachycardia (VT) or fibrillation (VF) in ischemic and nonischemic cardiomyopathy. The use and implications of LCSD on pediatric patients with congenital heart disease are not known. Bonura and colleagues (DOI: https://doi.org/10.1016/j.hrcr.2019.04.007) described two pediatric patients that underwent LCSD in the setting of refractory ventricular arrhythmias and congenital heart disease.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
In the evaluation of syncope, history is most important to arrive at a diagnosis.The first step is to confirm whether its truly a syncope or (Metabolic/TIA or seizure. We are easily carried away by the urge to order a Holter monitoring routimely. In reality, the yield is too low (3-5sec Or it may lead to Brady (Pause) dependent escape VT. A pause can be a sinus arrest, Pause or SA block .If pause ends with a junctional escape it becomes a arrest. Look PR interval specifically(A bifasicular block shouldn’t be missed .It can be more dangerous than say a congenital CHB)PR interal represents condcution from SA node to Pu...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Uncategorized Source Type: blogs
The sympathetic nervous system plays an important role in arrhythmogenesis in arrhythmogenic right ventricular cardiomyopathy (ARVC). Sudden cardiac death commonly occurs during exertion and beta-blockers are associated with reduction in arrhythmia burden. Bilateral cardiac sympathetic denervation (BCSD) has been shown to reduce implantable cardioverter-defibrillator (ICD) shocks in patients with structural heart disease and refractory ventricular tachycardia (VT), however data in ARVC are sparse.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
ConclusionThe loss of parasympathetic modulation was present in all Rassi risk groups, including the low‐risk, indicating that a morphological change of the myocardio represents a detectable neuro‐functional change.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: ELECTROPHYSIOLOGY Source Type: research
AbstractPurpose of ReviewVentricular arrhythmias (VAs) are a significant cause of morbidity and mortality in patients with cardiomyopathy (CM). This review focuses on ventricular tachycardia (VT) management in uncommon causes of heart disease, such as inflammatory and infiltrative CMs.Recent FindingsIntegration of advanced cardiac imaging modalities, such as cardiac magnetic resonance imaging (MRI) and positron emission tomography (PET), into diagnostic evaluation of patients with CM may unmask abnormal myocardial substrate in almost half of patients presenting with VAs. Stepwise approach to management of VAs in cardiac sa...
Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research
Short Notes PP interval is the interval between the P waves due to atrial depolarization (measured from the onset of one P wave to the onset of the next P wave). PP interval is used to calculate the atrial rate. In sinus rhythm, PP interval and RR interval are the same. Hence atrial rates and ventricular rates are not calculated separately. But when there is AV (atrioventricular) dissociation as in complete heart block, atrial rate is different from the ventricular rate. In complete heart block, PP interval is shorter than the RR interval, meaning that atrial rate is higher than the ventricular rate. In ventricular ...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Heart Disease FAQ Source Type: blogs
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
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