Impact of Baseline Left Ventricular Diastolic Dysfunction in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation

Diastolic dysfunction (DD) is a common finding in severe aortic stenosis (AS) patients.1 Myocardial remodeling eventually affects left ventricular (LV) relaxation, therefore impairing LV diastolic function with an increase in left atrial (LA) pressure, ultimately causing pulmonary congestion and symptoms of heart failure.2,3 Relief of stenosis through transcatheter aortic valve implantation (TAVI) results in reverse remodeling of the left ventricle, regression of LV hypertrophy, and improvement of LV systolic function.

Source: The American Journal of Cardiology - October 28, 2019 Category: Cardiology Authors: Edward Koifman, Diego Medvedofsky, Romain Didier, Rebecca Torguson, Zack Jerusalem, Sarkis Kiramijyan, Itsik Ben-Dor, Zuyue Wang, Steven A. Goldstein, Linzhi Xu, Augusto D. Pichard, Lowell F. Satler, Ron Waksman, Federico M. Asch Source Type: research