Clinical translation of the assets of biomedical engineering - a retrospective analysis with looks to the future.

Clinical translation of the assets of biomedical engineering - a retrospective analysis with looks to the future. Expert Rev Med Devices. 2019 Oct 28;: Authors: Ren Y, Fagette PH, Hall CL, Broers H, Grainger DW, van der Mei HC, Busscher HJ Abstract Introduction: Biomedical-engineering (BME) plays a major role in modern medicine. Many BME-based assets have been brought to clinical translation in the 20th century, but translation currently stagnates. Here, we compare the impact of past and present scientific, economic and societal climates on the translation of BME-based assets, in order to provide the BME-community with incentives to address current stagnation. Areas covered: In the 20th century, W.J. Kolff brought kidney dialysis, the total artificial heart, artificial vision and limbs to clinical application. This success raises the question whether Kolff and other past giants of clinical translation had special mind-sets, or whether their problem selection, their training, or governmental and regulatory control played roles. Retrospective analysis divides the impact of BME-based assets to clinical application into three periods: 1900-1970: rapid translation from bench-to-bedside, 1970-1990: new diseases and increased governmental control, and the current translational crisis from 1990 onward. Expert opinion: Academic and societal changes can be discerned that are concurrent with BME's translational success: mono-disciplinary versus...
Source: Expert Review of Medical Devices - Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research