Captaining the PIDD ship

As the review in this issue of the Annals makes clear, patients with common variable immunodeficiency (CVID) may exhibit one or more of a multiplicity of autoimmune diatheses involving any body system.1 The association of primary immunodeficiency diseases (PIDD) and autoimmunity is not restricted, however, to CVID.2 Similar associations between immunodeficiency and malignancy have been extensively reported as well.3 Our immunodeficiency patients are not merely subject to an increased incidence of the entire spectrum of common and exotic infections but to a panoply of life-threatening conditions that exceed the capacity of even the most broadly trained and astute immunologist.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research