Contraceptive efficacy of sperm agglutinating factor from Staphylococcus warneri, isolated from the cervix of a woman with inexplicable infertility.
CONCLUSION: The Sperm Agglutinating Factor from Staphylococcus warneri, natural microflora of human cervix, showed extensive potential to be employed as a safe vaginal contraceptive. PMID: 31656198 [PubMed - in process]
In conclusion, the aqueous extract A. africanus has anti-implantation effect in female rats and is safe up to 2000 mg/kg bw. In addition, it contains some potential steroidal saponins, which could be used to explain its an ti-implantation activity, however this finding needs further pharmacological studies to confirm the antifertility activities.
Condition: Urinary Tract Infections Interventions: Drug: LBP-EC01; Drug: Lactated Ringers Solution for Injection Sponsor: Locus Biosciences Not yet recruiting
Condition: Infertility Intervention: Behavioral: Physician phone call Sponsor: Boston IVF Not yet recruiting
Conditions: Gestational Diabetes Mellitus; Medical Nutrition Therapy; Overweight/Obese; Gut Microbiota; Adverse Pregnancy Outcomes Interventions: Dietary Supplement: Prebiotic-containing dairy; Dietary Supplement: Dietary intervention Sponsor: Capital Medical University Recruiting
Condition: Miscarriage Intervention: Sponsor: University Hospital, Montpellier Not yet recruiting
What strategies may help prevent the sexual transmission of Zika virus infection during pregnancy?Emerging Infectious Diseases
Funding Opportunity PAR-20-072 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Program Project (P01) applications. The proposed programs may address scientific areas relevant to the NIAID mission including the biology, pathogenesis, and host response to microbes, including HIV; the mechanisms of normal immune function system development and function; and immune dysfunction resulting in autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics t...
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jörg Kleine-Tebbe, Claudia Mailänder
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Marta Vazquez-Ortiz, Laura Argiz, Adrianna Machinena, Luis Echeverria, Cristina Blasco, Ana Prieto, Sonsoles Infante, Leticia Vila, Emilio Garcia, Purificación Gonzalez-Delgado, Sonia Vazquez-Cortes, Simona Barni, Frederico Martinon-Torres, BIO-FPIES study network
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Yumiko Miyaji, Limin Yang, Kiwako Yamamoto-Hanada, Masami Narita, Hirohisa Saito, Yukihiro Ohya