Inhibition of NET formation by polydatin protects against collagen-induced arthritis.

CONCLUSION: In this study, we found that PD treatment markedly inhibited NET formation and protected CIA mice from the development of arthritis. These findings suggest that inhibition of NET formation by PD may serve as a novel mechanism for the treatment of RA.
PMID: 31655341 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - October 22, 2019 Category: Allergy & Immunology Authors: Yang F, Luo X, Luo G, Zhai Z, Zhuang J, He J, Han J, Zhang Y, Zhuang L, Sun E, He Y Tags: Int Immunopharmacol Source Type: research