Stem Cells from Human Exfoliated Deciduous Teeth: A Concise Review.

Stem Cells from Human Exfoliated Deciduous Teeth: A Concise Review. Curr Stem Cell Res Ther. 2019 Oct 18;: Authors: Ko CS, Chen JH, Su WT Abstract Stem cells from human exfoliated deciduous teeth (SHED) originate from the embryonic neural crest as ectodermal mesenchymal stem cells and are isolated from human deciduous teeth.SHED expresses the same cell markers as embryonic stem cells (ESCs), such as OCT4 and NANOG, which make SHED have a significant impact on clinical applications. SHED possess higher rates of proliferation, higher telomerase activity, increased cell population doubling,form sphere-like clusters, and possess immature and multi-differentiation capacity; such high plasticity make SHED is one ofthe most popular source of stem cells for biomedical engineering. In this review, we describe the isolation and banking method, current development of SHEDin regenerative medicine and tissue engineering in vitro and in vivo. PMID: 31648649 [PubMed - as supplied by publisher]
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research