DNA Replication Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency

Conclusion: A complex circuitry between retinoic acid signaling, SWI/SNF components, pluripotency factors including Oct4, Sox2 and Nanog and cell cycle regulators was identified. It is suggested that the DNA replication inhibitor geminin plays a central role in this circuitry.

Source: Cancer Genomics and Proteomics - October 27, 2019 Category: Cancer & Oncology Authors: TSANIRAS, S. C., DELINASIOS, G. J., PETROPOULOS, M., PANAGOPOULOS, A., ANAGNOSTOPOULOS, A. K., VILLIOU, M., VLACHAKIS, D., BRAVOU, V., STATHOPOULOS, G. T., TARAVIRAS, S. Tags: Article Source Type: research