How Common Are Gastric Ulcers?
Discussion The exact cause of gastric and upper intestinal inflammation and ulceration are not entirely understood. Imbalances between irritative factors and mucosal defenses underlie it. Gastric acid production is at adult levels by 3-4 years. Actual ulceration is associated with a lower acid secretion for gastric ulcerations but are increased in duodenal ulcerations in both adults and children. In adults changes to the mucus layer of the stomach and duodenum and bicarbonate secretion play a part in upper GI inflammation and ulcerations. Genetic studies have been linked to differences in both acid production, and mucosal barriers. Additionally there may also be genetic differences linked to Helicobacter pylori (H. pylori) infections. H. pylori infections are linked to overcrowding and poor socioeconomic conditions, but rates appear to be declining across the world. Primary ulcerations are defined as upper GI ulcerations in pediatric patients that have no other identified etiology. They are most often caused by H. pylori infection in children. They are much less frequent than secondary ulcerations. Secondary ulcers are due to other causes of upper GI inflammation such as trauma, sepsis, or drugs (i.e. non-steroidal anti-inflammatory drugs), but they can also occur as a secondary problem in specific diseases such as Crohn’s disease and Zollinger-Ellison syndrome. Sickle-cell anemia, reactivation of viral infections such as Epstein-Barr and Varicella infections, and cyst...
CONCLUSION: Splenic fibrosis progresses along with advancement of PH. Cygb-expressing cells in the splenic cord possibly participate in this process through mechanisms including oxidative stress. PMID: 32945524 [PubMed - as supplied by publisher]
Publication date: Available online 19 September 2020Source: Journal of Pharmacological SciencesAuthor(s): Lei Li, Daisuke Nakano, Anqi Zhang, Wararat Kittikulsuth, Norihiko Morisawa, Hiroyuki Ohsaki, Norio Suzuki, Masayuki Yamamoto, Akira Nishiyama
Authors: Signorelli F, Montano N Abstract Hemostasis plays a central role throughout neurosurgery. In microneurosurgery, a bloodless operating field under an operating microscope allows fast and effective surgery, thereby reducing the risk of postoperative hemorrhage. Apart from mechanical methods, such as positioning of the patient's head and body, bone plugging, suction, and metal clips, neurosurgical hemostasis is achieved mainly with bipolar coagulation, which permits optimal control of hemorrhage, allows for fine coagulation of small vessels and is safe in patients with pacemakers and defibrillators. Gelatin s...
Conclusions: CT-guided blood tattoo is a safe option for localization of nonpleural-based lung nodules prior to thoracoscopic excision in pediatric patients. PMID: 32944340 [PubMed]
Conclusions: The ultrasound sliding lung sign could be used to predict severe intrathoracic adhesions before surgery. Preoperative confirmation of the ultrasound sliding lung sign is important for planning surgical approaches and implementing appropriate safety management. PMID: 32944334 [PubMed]
Conclusions: Both 3D image reconstruction and thin-section MDCT provided precise preoperative information about SA. The 3D image reconstruction software "Exoview" could visualize SA for surgeons. However, the thin-section MDCT provided a better evaluation of small SA branches. PMID: 32944331 [PubMed]
Authors: Shim JG, Ryu KH, Kim PO, Cho EA, Ahn JH, Yeon JE, Lee SH, Kang DY Abstract Background: Video-assisted thoracoscopic surgery (VATS) is a commonly performed minimally invasive procedure that has led to lower levels of pain, as well as procedure-related mortality and morbidity. However, VATS requires analgesia that blocks both visceral and somatic nerve fibers for more effective pain control. This randomized controlled trial evaluated the effect of erector spinae plane block (ESPB) in the postoperative analgesia management of patients undergoing VATS. Methods: We performed a prospective, randomized, singl...
Authors: Xu Y, Li XK, Zhou H, Cong ZZ, Wu WJ, Qiang Y, Shen Y Abstract Background: Paravertebral block (PVB) conducted by epidural catheter is a prevalent pain management for patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy. The aim of this study was to assess the efficacy and safety of paravertebral block with a modified PVB (MPVB) catheter under surgeon's direct vision after video-assisted thoracoscopic lobectomy. Methods: Three hundred fifty-six patients undergoing VATS lobectomy were retrospectively reviewed and divided into two groups consecutively according to the catheter applied...
Authors: Donadio MVF, Vendrusculo FM, Pérez-Ruiz M PMID: 32944304 [PubMed]
Conclusions: The "Firefly" app based sensing technology offers the potential to significantly lower the barrier of entry to OSA screening, as no hardware (other than the user's personal smartphone) is required. Additionally, multi-night analysis is possible in the home environment, without requiring the wearing of a portable PSG or other home sleep test (HST). PMID: 32944361 [PubMed]
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