An in vitro experimental study of the effect of fosfomycin in combination with amikacin, ciprofloxacin or meropenem on biofilm formation by multidrug-resistant urinary isolates of Escherichia coli.

Conclusion. The combination of fosfomycin with amikacin and fosfomycin with meropenem yielded a high percentage of synergy alongside an increased capacity to reduce biofilm formation when compared to combination with ciprofloxacin against multidrug-resistant E. coli. Fosfomycin in combination with other classes of antimicrobial agents has potential beneficial effects. PMID: 31647407 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31647407?dopt=Abstract

Source: Journal of Medical Microbiology - October 23, 2019 Category: Microbiology Authors: Sugathan S, Mandal J Tags: J Med Microbiol Source Type: research