Superior role of waist circumference to body-mass index in the prediction of cardiometabolic risk in dyslipidemic patients.

Superior role of waist circumference to body-mass index in the prediction of cardiometabolic risk in dyslipidemic patients. Physiol Res. 2019 Oct 25; Authors: Cibičková Ľ, Langová K, Vaverková H, Lukeš J, Cibiček N, Karásek D Abstract Coronary risk evaluation by conventional factors (age, gender, smoking, blood pressure and cholesterol) may further be specified by facets of the metabolic syndrome, namely insulin resistance, hypertriglyceridemia and obesity. Although obesity is usually defined as elevated body mass index (BMI), recent data indicate a superior role of waist circumference or hypertriglyceridemic waist (HTGW) over BMI in the assessment of cardiometabolic risk. In dyslipidemic patients, the specific contributions of risky waist, HTGW or BMI have not been evaluated as yet. 686 dyslipidemic subjects (322 males and 364 females) were enrolled into a cross-sectional study. In each subject basic antropometry (i.e. waist circumference, HTGW, BMI) and laboratory parameters of lipid profile and insulin resistance were determined. Cardiometabolic risk was given by fulfilling the criteria (harmonized definition) of metabolic syndrome. The significance of risky waist, HTGW and BMI were assessed by comparing the respective predictive values for the presence of metabolic syndrome. Dyslipidemic patients with risky waist, HTGW or high BMI have a more atherogenic lipid profile and higher insulin resistance compared to those withou...
Source: Physiological Research - Category: Physiology Authors: Tags: Physiol Res Source Type: research