Two novel mixed-ligand zinc-acesulfame compounds: synthesis, spectroscopic and thermal characterization and biological applications

Publication date: Available online 25 October 2019Source: Journal of Molecular StructureAuthor(s): Ömer Yurdakul, Dursun Ali Köse, Onur Şahin, Gülçin Alp AvcıAbstractTwo new tetrahedral acesulfame complexes, acesulfamato(N)acesulfamato(O)bis(3-aminopyridine) zinc(II) (C18H20N6O8S2Zn, Zn-ace-3ap) and bis(acesulfamato-O)bis(benzotriazole)zinc(II) (C20H18N8O8S2Zn, Zn-ace-bta), were synthesized and characterized by single crystal X-ray diffraction, FT-IR spectroscopy, elemental analysis and thermal analysis techniques(TGA, DTA, DTG). The first compound, Zn-ace-3ap, crystallizes in triclinic space group P1 with parameters a=7.978 (7) Å, b=9.907 (6) Å, c=15.778 (14) Å, α=78.24° (2), β =81.22° (4), γ=75.99° (2), Z=2 and The second compound, Zn-ace-bta, crystallizes in monoclinic space group C2/c with parameters a=19.879 (3) Å, b=9.3637 (13) Å, c=14.0852 (18) Å, β=105.483° (4), Z=4. The biological activities of the synthesized complexes were appraised through disk diffusion method as antibacterial, antimicrobial and antifungal in DMSO. Enterococcus faecalis (ATCC-29212), Staphylococcus aureus (ATCC-25923) as gram-positive bacteria, Pseudomonas aeroginosa (ATCC-27853) and Escherichia coli (ATCC-25922) as gram-negative bacteria, and Candida albicans (ATCC-10231) as fungus were grown with a view to investigate the antimicrobial effects of the complexes.
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research