Can dynamic contrast-enhanced ultrasound (DCE-US) improve diagnostic performance in endometrial cancer staging? A proof of concept.

CONCLUSION: Combining DCE-US with 2D-TVU/PD can significantly improve the detection of deep MI and CSI without increasing the false positive rate compared to using 2D-TVU alone. It can also improve the correct classification of high-risk disease mainly by increasing the specificity and thereby possibly avoid unnecessary surgeries by almost ten percent. Quantitative DCE-US parameters, as well as a 'focal' filling pattern, endometrial wash-in 'prior' to the myometrium and a 'focal' wash-out pattern, all correlate to more advanced disease. This article is protected by copyright. All rights reserved. PMID: 31647145 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research