Hormone Replacement for Pelvic Floor Disorders

AbstractPurpose of ReviewThe purpose of this review article is to summarize the recent literature regarding the effect of hormone replacement therapy on pelvic floor disorders and its role as a preventative or treatment option.Recent FindingsThe recent evidence describing the effect of hormone replacement therapy on pelvic floor disorders is mainly limited to cohort studies, systematic reviews, and secondary analysis of randomized controlled trials such as the Women ’s Health Initiative and Nurses’ Health Study. There are few quality randomized controlled trials, especially within the last 5 years on this topic. The data that does exist does not show hormone therapy to be beneficial in the treatment or prevention of pelvic floor disorders. In fact, it may worsen urinary and fecal incontinence when given systemically. The exception to this is the local application of vagina estrogen, where it may be of some benefit in the treatment of urinary incontinence. Local application has been shown to be beneficial when treating genitourinary syndrome of menopa use and in the prevention of recurrent urinary tract infections.SummaryThere is a paucity of quality data regarding the secondary effects and use of hormone replacement as a treatment for pelvic floor disorders. Given the lack of studies, limited efficacy, and possible side effects, it should not be offered as first-line or single treatment for pelvic floor disorders such as urinary or fecal incontinence and pelv...
Source: Current Bladder Dysfunction Reports - Category: Urology & Nephrology Source Type: research

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ConclusionThis surgery achieves high healing rates, with few complications, improvement of subjective symptoms and high level of satisfaction of the patients.ResumenIntroducción y objetivoEl riesgo de intervención por prolapso urogenital en la vida de una mujer es del 11,1%. Las recidivas después de la cirugía clásica alcanzan el 38%. Para tratar de mejorar estos resultados se usan kits de mallas de polipropileno transvaginales. El propósito del estudio es describir los resultados de eficacia y seguridad a largo plazo de la cirugía de prolapsos vaginales con mallas de polipr...
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research
This study also found that Proteus DNA, a genus with many uropathogenic species (Drzewiecka, 2016), was more prevalent in women with OAB compared to asymptomatic controls (Curtiss et al., 2017). IC A recent study by Abernethy et al. suggested that the microbiome may play a role in IC (Abernethy et al., 2017). In this study, 16S rRNA analysis determined the microbiome of catheterized urine from women (n = 40) with IC was not dominated by a single genus and was less likely to contain Lactobacillus compared to asymptomatic women. Abernethy et al. also showed that L. acidophilus was associated with less severe scores on the ...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Kate V. Meriwether1*, Zhenmin Lei1, Rajbir Singh2, Jeremy Gaskins3, Deslyn T. G. Hobson1 and Venkatakrishna Jala2 1Department of Obstetrics and Gynecology, University of Louisville, Louisville, KY, United States 2Department of Microbiology and Immunology, James Graham Brown Cancer Center, University of Louisville, Louisville, KY, United States 3Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY, United States Interstitial cystitis/bladder pain syndrome (ICBPS) may be related to an altered genitourinary microbiome. Our aim was to compare the vaginal and urinary microbiomes b...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
CONCLUSION: This surgery achieves high healing rates, with few complications, improvement of subjective symptoms and high level of satisfaction of the patients. PMID: 30955903 [PubMed - as supplied by publisher]
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Authors: Tags: Actas Urol Esp Source Type: research
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Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Letter to Editor Source Type: research
Authors: Isaza PG Abstract Vulvo-vaginal atrophy as a main symptom of the Genito Urinary Syndrome of Menopause (GSM) is a consequence of aging, particularly after menopause as a result of follicular ovarian follicle depletion and consequently low estrogen levels. Anatomical structures derived from the urogenital sinus, such as the distal urethra trigone and vestibule, are the most affected areas because of the high concentrations of alfa- and beta-estrogen receptors. The most common symptoms associated with vulvo-vaginal atrophy are dyspareunia, vaginal dryness, irritation, recurrent urinary tract infection and uri...
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research
Authors: Arribillaga L, Bengió RG, Ledesma M, Montedoro A, Orellana S, Pisano F, Bengió RH Abstract INTRODUCTION: Various authors argued that the voiding urgency component in mixed urinary incontinence (MUI) is different than urge urinary incontinence (UUI). In this last case they suggest that incontinence in MUI could be overdiagnosed in patients with SUI, misunderstanding the leak as UUI. OBJETIVES: To evaluate clinical and urodynamic characteristics of patients with MUI and pure UUI. METHODS: A retrospective study of our urodynamics database was performed evaluating 450 women with MUI and U...
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
Conclusions Correction of SUI using TOT appears to have a positive effect on female sexual function.
Source: Arab Journal of Urology - Category: Urology & Nephrology Source Type: research
This article will review the effect of oral contraceptive pills on bladder symptoms.Recent FindingsOral contraceptives appear to decrease the risk of stress urinary incontinence (SUI). The effect of OCP on recurrent UTI, OAB/UUI is unclear. Combined oral contraceptives may be implicated in interstitial cystitis/bladder pain syndrome.SummaryThere appears to be a link between changes in estrogen and progesterone levels and lower urinary tract symptoms. While many studies have evaluated the effect of hormones on the genitourinary tract and bladder function in postmenopausal women menopause, further studies are needed to direc...
Source: Current Bladder Dysfunction Reports - Category: Urology & Nephrology Source Type: research
Conclusion Urinary tract infection after midurethral sling procedures is a relatively common complication. The presence of preoperative urinary tract infection, TVT procedure and postoperative postvoiding residual bladder volume ≥100ml may increase the risk of this complication. Identification of these factors could help surgeons to minimize this complicationby developing effective strategies.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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