Influence of inter-field communication on neuronal response synchrony across auditory cortex.

Influence of inter-field communication on neuronal response synchrony across auditory cortex.
Hear Res. 2013 Jun 18;
Authors: Carrasco A, Lomber SG
Abstract
Sensory information is encoded by cortical neurons in the form of synaptic discharge time and rate level. These neuronal codes generate response patterns across cell assemblies that are crucial to various cognitive functions. Despite pivotal information about structural and cognitive factors involved in the generation of synchronous neuronal responses such as stimulus context, attention, age, cortical depth, sensory experience, and receptive field properties, the influence of cortico-cortical connectivity on the emergence of neuronal response patterns is poorly understood. The present investigation assesses the role of cortico-cortical connectivity in the modulation of neuronal discharge synchrony across auditory cortex cell-assemblies. Acute single-unit recording techniques in combination with reversible cooling deactivation procedures were used in the domestic cat (Felis catus). Recording electrodes were positioned across primary and non-primary auditory fields and neuronal activity was measured before, during, and after synaptic deactivation of adjacent cortical regions in the presence of acoustic stimulation. Cross-correlation functions of simultaneously recorded units were generated and changes in response synchrony levels across cooling conditions were measured. Data analyses reveale...

Source: Hearing Research - June 18, 2013 Category: Audiology Authors: Carrasco A, Lomber SG Tags: Hear Res Source Type: research