Comparison of In Vitro and In Vivo Percutaneous Absorption Across Human Skin Using BAY1003803 Formulated as Ointment and Cream

In conclusion, in vitro skin absorption studies using human skin are suitable for the prediction of systemic exposu re and formulation effects in vivo; they can therefore be applied to guide the design of clinical investigations of dermatological preparations.

Source: Clinical Pharmacology in Drug Development - October 23, 2019 Category: Drugs & Pharmacology Authors: Clemens G ünther, Kristin Kowal, Timm Schmidt, Alen Jambrecina, Frank Toner, Rüdiger Nave Tags: Original Manuscript Source Type: research