Alzheimer's Disease And Retinal Degeneration: A Glimpse At Essential Trace Metals In Ocular Fluids And Tissues.

CONCLUSION: Hence, this review address current knowledge about some up-to-date investigated essential trace metals associated with AD and AMD. Changes in the levels of systemic and ocular fluid essential metals might reflect the early stages of AMD, possibly disclosing neurodegeneration pathways shared with AD, which might open to potential early detection. PMID: 31642780 [PubMed - as supplied by publisher]
Source: Current Alzheimer Research - Category: Neurology Authors: Tags: Curr Alzheimer Res Source Type: research

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Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/C9CC08267K, CommunicationSongjiao Li, Peipei Wang, Wenqi Feng, Yunhui Xiang, Kun Dou, Zhi-hong Liu Alzheimer ’s disease (AD) is an irreversible neurodegenerative disorder that has a progression closely associated with oxidative stress. It has been speculated that both the intracellular viscosity and H2O2 level in... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
árquez MÁ, Baranda-Tovar FM PMID: 31834325 [PubMed - in process]
Source: Archivos de Cardiologia de Mexico - Category: Cardiology Authors: Tags: Arch Cardiol Mex Source Type: research
, Jacobo-García K, Cossio-Aranda J Abstract Heart failure (HF) is a syndrome characterized basically by a circulatory deficit to cover the metabolic and energetic demands of the body. This condition has a broad spectrum in its clinical presentation, affects the quality of life significantly, impacts the family/social environment, and generates a great demand for health services. The purpose of this research is to report the situational diagnose of patients with HF in Mexico. We evaluated 292 patients, 70.2% were men. Average age was 56.7 ± 14.3 years. Ischemic heart disease is the main etiology (98 p...
Source: Archivos de Cardiologia de Mexico - Category: Cardiology Authors: Tags: Arch Cardiol Mex Source Type: research
Conclusion: The overall incidence of VTE is 4% with more than half of events occurred after the stoppage of thromboprophylaxis highlighting the necessity of adopting an extended protocol. Independent predictors included older age, female gender, morbid obesity and preoperative thrombocytosis. These group of patients require particular attention for the prevention of this complication. PMID: 31830847 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Rui Liu, Chan Wei, Qiang Ma, Weimin WangAbstractBackgroundThe present study aims to explore the possible mechanisms of Hippo-YAP1 signaling pathway in the development of severe preeclampsia (sPE).MethodsA total of 14 pregnancies complicated with severe preeclampsia as well as 14 healthy pregnancies were involved in this research from Department of Obstetrics, the First Affiliated Hospital of Xi’An Jiaotong University, from 15th March 2016 to 15th March 2018. The mRNA levels of YAP1, TAZ, MST1 and MST2 were tested via the RT-qPCR in the ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
In conclusion, intake of carbohydrate, protein, fiber, thiamin, riboflavin, niacin, and vitamin C was associated with decreased severity of airway impairment in elderly men with COPD. Our results are in line with those of previous studies into the importance of nutritional status in airway disease. A longitudinal study is required to clarify the mechanisms underlying the association between dietary nutrient intake and COPD severity. PMID: 31833439 [PubMed - as supplied by publisher]
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Publication date: Available online 13 December 2019Source: Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAuthor(s): Jerónimo Lazos, Eugenia Rodríguez Marco, Mabel Brunotto, Rene Panico, Eduardo PiemonteAbstractObjectiveOral venous varicosities (OV) are a common condition, increasing its incidence with age. They are also mentioned in association with several medical conditions, but the evidence is scarce and inconsistent. The aim was to describe OV clinical features and to analyze the association with medical conditions.MethodsAn observational, cross-sectional study was carried out in the O...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
Publication date: Available online 14 December 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Alessandra Feraco, Vincenzo Marzolla, Angelo Scuteri, Andrea Armani, Massimiliano CaprioOver the past decade, several studies have shown that activity of extra-renal mineralocorticoid receptors (MR) regulates vascular tone, adipogenesis, adipose tissue function, and cardiomyocyte contraction. In mice, abnormal activation of MR in the vasculature and in adipose tissue favors the occurrence of several components of the metabolic syndrome (MetS), such as hypertension, obesity, and glucose intolerance. Accordingly, high...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 13 December 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Jiaojiao Hu, Huiyong Sun, Haiping Hao, Qiuling ZhengAbstractAmyloid fibrils are found in systemic amyloidosis diseases such as Alzheimer's disease, Parkinson's disease, and type II diabetes. Currently, these diseases are diagnosed by observation of fibrils or plaques, which is an ineffective method for early diagnosis and treatment of disease. The goal of this study was to develop a simple and quick method to predict the possibility and speed of fibril formation before its occurrence. Oligomers generated from seven repre...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
ConclusionJiao-tai-wan has the potential to attenuate systemic inflammation and cognitive impairment in partially sleep-deprived rats. The possible underlying mechanism is by preventing an inflammation trigger being transferred through the gut-brain-axis.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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