Genetic Obesity and Bariatric Surgery Outcome in 1014 Patients with Morbid Obesity

ConclusionsIn this cohort of morbid obese bariatric patients, an estimated prevalence of monogenic obesity of 3% is reported. Among these patients, the clinical effects of heterozygous mutations inPOMC andPCSK1 do not interfere with the effectiveness of most commonly performed bariatric procedures within the first 2  years of follow-up. Patients withMC4R mutations achieved superior weight loss after primary RYGB compared with SG.
Source: Obesity Surgery - Category: Surgery Source Type: research