White matter alterations in early Parkinson ’s disease: role of motor symptom lateralization

ConclusionWM integrity was found to be significantly altered in RPD but not in LPD, suggesting that LPD profile may be associated to more favorable prognosis. Since clinical laterality onset may affect the extent of WM integrity changes, it should be taken into account in neuroimaging studies investigating PD.

http://link.springer.com/10.1007/s10072-019-04084-y

Source: Neurological Sciences - October 23, 2019 Category: Neurology Source Type: research