Long-term Outcomes of Mechanical Vs Biologic Aortic Valve Prosthesis in Patients Older Than 70 Years

This study investigated differences in long-term outcomes between SAVR-treated patients more than 70 years of age who received mechanical or biologic prosthetic valves.MethodsAll patients (excluding those with endocarditis) who were more than 70 years of age and who underwent isolated first-time SAVR (with or without coronary artery bypass grafting) in Finland between 2004 and 2014 were retrospectively studied (n = 4227). Propensity score matching (1:3) was used to account for baseline differences (n = 296 with mechanical prostheses and n = 888 with biologic prostheses). Outcomes were 10-year survival, major bleeding (all, gastrointestinal, intracranial), ischemic stroke, infective endocarditis, and aortic valve reoperation. Mean age was 75.8 years, and mean follow-up was 8.3 years.ResultsSurvival at 10 years was 46.1% with mechanical prostheses and 57.8% with biologic prostheses (hazard ratio [HR], 1.48; 95% confidence interval [CI], 1.21 to 1.80; P 
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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Publication date: Available online 9 December 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): I Laffont, J Froger, C Jourdan, K Bakhti, LEH Van Dokkum, A Gouaich, HY Bonnin, P Armingaud, A Jaussent, MC Picot, E Le Bars, A Dupeyron, C Arquizan, A Gelis, D MottetAbstractBackground. Few rehabilitation methods have proven their efficacy in increasing sensori-motor recovery and/or function of the upper limb (UL) after stroke. Video games (VGs) are promising tools in this indication.Objective. To compare UL rehabilitation by using VGs and conventional rehabilitation (CR) in patients with sub-acute stroke.Des...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 9 December 2019Source: NeuropsychologiaAuthor(s): Fang Wang, Urs MaurerAbstractHow and when top-down information modulates visual-orthographic processing is an essential question in reading research. In a previous study, we showed that task modulation of print-tuning started at around 170 ms after stimulus presentation in the N1 offset of the ERP, while the N1 onset was yet unaffected. Here we test how prior category-level expectation affects visual-orthographic processing. Familiar, left/right-structured Chinese characters and stroke number matched, unfamiliar Korean characters were pr...
Source: Neuropsychologia - Category: Neurology Source Type: research
Condition:   Stroke Intervention:   Other: Observational study Sponsors:   Parc de Salut Mar;   Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study included 1249 consecutive patients undergoing either transcatheter aortic valve implantation (TAVI), Mitraclip, left atrial appendage occlusion (LAAO) or paravalvular leak closure (PVLC). Patients were divided into two cohorts based on the degree of probe manipulation required to guide the procedure and the risk of developing a TEE-related complication: low-risk (TAVI, n = 1037) and high-risk (Mitraclip, LAAO and PVLC, n = 212). Patients were further analyzed according to the occurrence of major and minor TEE-related complications.ResultsThe overall incidence of TEE-related complications was ...
Source: American Heart Journal - Category: Cardiology Source Type: research
What are the current trends and hot topics in neurology? The increasing insights into the genetics and molecular bases of neurological disorders open new perspectives for specific and personalized treatments. This is evidenced most dramatically by the antisense therapy for spinal muscular atrophy. Promising neurological research currently targets neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Duchenne muscular atrophy, or Huntington’s disease. Likewise, brain-machine interfaces and neuroprosthetics offer huge potential. Never before has it been more important and more exc...
Source: BioMed Central Blog - Category: General Medicine Authors: Tags: Uncategorized Source Type: blogs
We report a young man presenting recurrent ischemic strokes with selective finger weakness in whom serial motor cortex mapping procedures were performed.ResultFollowing the first stroke, which largely spared the motor cortex, motor mapping displayed overlap of the motor representations of the hand muscles. The second focal stroke, affecting the lateral part of the hand knob, resulted in selective loss of the first dorsal interosseous muscle motor evoked potentials while sparing those of the adductor digiti minimi muscle. This observation is in apparent contradiction with the first mapping results that suggested complete ov...
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
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Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 10 May 2019Source: The Annals of Thoracic SurgeryAuthor(s): Ville Kytö, Monna E. Myllykangas, Jussi Sipilä, Teemu J. Niiranen, Päivi Rautava, Jarmo GunnAbstractBackgroundBiological prostheses are preferred for surgical aortic valve replacement (SAVR) in patients aged>70 years in clinical practice. We studied differences in long-term outcomes between SAVR patients aged>70 years who received mechanical and biological prosthetic valves.MethodsAll patients (excluding endocarditis) aged>70 years with isolated first-time SAVR (±coronary artery by-pass grafting) in...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Long-term outcomes with mechanical versus biological aortic valve prosthesis in patients>70 years. Ann Thorac Surg. 2019 May 10;: Authors: Kytö V, Myllykangas ME, Sipilä J, Niiranen TJ, Rautava P, Gunn J Abstract BACKGROUND: Biological prostheses are preferred for surgical aortic valve replacement (SAVR) in patients aged>70 years in clinical practice. We studied differences in long-term outcomes between SAVR patients aged>70 years who received mechanical and biological prosthetic valves. METHODS: All patients (excluding endocarditis) aged>70 years with isolated first-time SA...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Conclusion Early cardiac surgery in patients with infective endocarditis and stroke maybe lifesaving with a low neurological risk. Comprehensive neurovascular imaging may help in identifying patient-related risk factors.
Source: Asian Cardiovascular and Thoracic Annals - Category: Cardiology Authors: Tags: Cardiac Source Type: research
More News: Bleeding | Cardiovascular & Thoracic Surgery | Coronary Artery Bypass Graft | Endocarditis | Finland Health | Gastroenterology | Heart Valve Surgery | Infective Endocarditis | Ischemic Stroke | Stroke | Study