Assessing recovery after cold challenge and thumb involvement can help to rule out systemic sclerosis in patients presenting with Raynaud's phenomenon.

Conclusions: In patients with RP, when there is restoration of perfusion in all fingers after 10 min or when the thumb is spared, the presence of an underlying SSc is very unlikely. Although these results need to be validated in a clinical setting in a larger prospective study, these signs can help physicians to select additional testing for SSc in RP patients. PMID: 31637927 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31637927?dopt=Abstract

Source: Scandinavian Journal of Rheumatology - October 21, 2019 Category: Rheumatology Authors: van Roon AM, van Roon AM, Stel AJ, Bootsma H, Smit AJ, Mulder DJ Tags: Scand J Rheumatol Source Type: research