Prophylaxis Against Early-onset Group B Streptococcus Infections in Pregnant Women Who Are Allergic to Penicillin
This article will review established screening techniques, intrapartum antibiotic prophylactic regimens, and management specifically of the penicillin-allergic pregnant woman who is colonized with GBS.
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Conclusion Alternative antibiotic use for GBS prophylaxis is frequent with penicillin/cephalosporin allergies. Efforts to confirm allergy and perform penicillin hypersensitivity testing may increase compliance with guidelines for antibiotic administration. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | open access Full text
Group B Streptococcus (GBS) or Streptococcus agalactiae are β-hemolytic gram-positive bacteria that colonize the lower genital tracts of women and are frequently associated with infections during pregnancy. Innate immune defenses are critical for controlling GBS dissemination and systemic infection. Mast cells are resident sentinel cells that come into cont act with pathogens early during colonization and infection.
What is the issue? A technique called vaginal seeding, sometimes used for babies born by caesarean section, "can give newborns deadly infections and sepsis," warns the Mail Online. Vaginal seeding involves rubbing vaginal fluid onto the skin of a newborn baby born by caesarean section. It's intended to mimic the natural transfer of microbes from their mother that babies have during a vaginal birth. This has been reported by some to help boost a baby's response against allergies and asthma. As many as 90% of Danish obstetricians and gynaecologists said they have been asked about it by prospective parents. Despite...
Conclusion This subgroup analysis of babies from a large Canadian birth cohort assessed whether exposure to furry pets before and after birth has any impact on infant gut bacteria. Overall it found that exposure to pets while in the womb and after birth was linked with richer and more diverse gut bacteria. The researchers say that several studies in the past, including their own, have found a link between richness of gut bacteria and both the development of allergies and the development of obesity. Therefore these findings may be taken to imply that pet exposure could protect against allergy and obesity in infants – ...
CONCLUSIONS: Unverified penicillin allergy is associated with more hospital utilization and additional morbidity. Penicillin allergy testing of pregnant women with a history of penicillin allergy may help reduce these unwanted outcomes. PMID: 28333608 [PubMed - in process]