Association of HSPA1B Polymorphisms with Paranoid Schizophrenia in a Polish Population

This study aimed to find the potential association betweenHSPA1B polymorphisms and risk of paranoid schizophrenia, clinical variables of the disease, and suicidal behavior. A total of 901 unrelated Polish subjects of Caucasian origin (377 schizophrenia patients and 524 controls) were recruited. Four single-nucleotide polymorphisms (SNP) were genotyped using PCR –RFLP (rs539689, rs9281590) and TaqMan assays (rs263979, rs6547452). A strong tendency towards statistical significance (p = 0.051) was observed in rs539689 allele distribution between patients and controls in overall study subjects. After stratification according to gender, we found that rs539689 was significantly associated with schizophrenia in males, but not in females. The minor allele C had a protective effec t in males [OR 0.73 (95% CI 0.61–0.88,p 
Source: NeuroMolecular Medicine - Category: Neurology Source Type: research

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(MediaSource) A multistate study of Medicaid enrollees led by researchers at The Ohio State University Wexner Medical Center found that suicide risk was highest among youth with epilepsy, depression, schizophrenia, substance use and bipolar disorder. In addition, the odds of suicide decreased among those who had more mental health visits within the 30 days before the date of suicide.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Basu S, Verma S, Abdin E Abstract Depression is commonly seen in the course of Schizophrenia and can occur during any of the phases of the psychotic illness. The present study examines the incidence of depression at baseline and De Novo depression in First episode of non-affective psychoses and the course of depression in the 12 months following first episode psychosis, any predictive significance of baseline depression with recurrence of depression in the subsequent phases of the psychotic illness. The study was conducted with a clinical sample of 460 patients under the care of a First episode psychosis p...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
Men and women experience schizophrenia differently; from the age of onset to symptoms and how society treats those with mental disorders.  Schizophrenic, Rachel Star Withers and co-host Gabe Howard continue the discussion of the differences from the last episode but change the focus to men.  Jason Jepson, an author who has schizophrenia joins for a man’s perspective and Dr. Hayden Finch returns to explain the clinical side of the issues. Highlights in “Schizophrenia in Men” Episode [01:30] Age of onset [04:00] Symptoms in men vs women [05:00] Interview with Jason Jepson [07:30] Jason discusses ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Inside Schizophrenia Men's Issues Psychiatry Psychology Living With Schizophrenia Mental Disorder Mental Health Mental Illness Symptoms Of Schizophrenia Source Type: blogs
BACKGROUND: Previous studies found several factors associated with suicide in schizophrenic patients, such as age, sex, education level, history of suicide attempts, psychotic symptoms, social factors, and substance abuse. However, there might be some addi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
  Are people with mental illness more creative? Jackie believes there may be a link between the two, while Gabe thinks it’s just a bunch of hoopla. Get ready — they’ve both done their research and are ready to back their claims. Tune in to hear a lively (and friendly) debate on whether the science is valid, the difference between inspiration and creativity, as well as their own opinions and experiences on mental illness and creativity. What’s your take? Join us on this Not Crazy podcast to see whose side you’re on, or if you’re somewhere in the middle. (Transcript Available Belo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Creativity Disorders General Mental Health and Wellness Not Crazy Podcast Schizophrenia Source Type: blogs
ConclusionsThe effects of climate change can be direct or indirect, short-term or long-term. Acute events can act through mechanisms similar to that of traumatic stress, leading to well-understood psychopathological patterns. In addition, the consequences of exposure to extreme or prolonged weather-related events can also be delayed, encompassing disorders such as posttraumatic stress, or even transmitted to later generations.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
The use of alcohol or drug(s) prior to self-injury is a possible inducing factor for suicidal self-injuries among patients with adjustment disorder. We analyzed the cases of 175 individuals who were admitted to the intensive care unit (ICU) of Tokyo Medica...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
We describe here a 22-year-old male Indian with decreased sleep, aggressive behaviour, self-muttering, disorganised behaviour, frequent spitting, biting and self-mutilation; he bit off his rig...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Authors: Takeuchi T, Okumura Y, Ichikura K Abstract The use of alcohol or drug(s) prior to self-injury is a possible inducing factor for suicidal self-injuries among patients with adjustment disorder. We analyzed the cases of 175 individuals who were admitted to the intensive care unit (ICU) of Tokyo Medical and Dental University Medical Hospital for suicidal self-injury to determine whether alcohol consumption or an excessive use of prescribed psychotropic medications prior to self-injury is more common in patients with adjustment disorder. During a 7-year period (July 2006 to June 2013) following their deliberate...
Source: Acta Medica Okayama - Category: General Medicine Tags: Acta Med Okayama Source Type: research
The objectives of this study are: (i) to assess the frequency of self-stigma in a multicentric nonselected psychiatric rehabilitation SMI and ASD sample; and (ii) to investigate the correlates of elevated self-stigma in different SMI conditions and in ASD. METHODS.: A total of 738 SMI or ASD outpatients were recruited from the French National Centers of Reference for Psychiatric Rehabilitation cohort (REHABase). Evaluations included sociodemographic data, illness characteristics, and standardized scales for clinical severity, quality of life, satisfaction with life, wellbeing, personal recovery, a large cognitive batte...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
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