MicroRNA-744/transforming growth factor β1 relationship regulates liver cirrhosis

ConclusionsMiR-744-led suppression in HSC activation is most likely through TGF β1 because exogenous TGFβ1 nearly negated miR-744 Agomir’s action. This study suggests that reduction of miR-744 is a reliable biomarker for LC and miR-744/TGFβ1 relationship is a key regulator of LC.
Source: Hepatology International - Category: Infectious Diseases Source Type: research