Delivery of cell membrane impermeable peptides into living cells by using head-to-tail cyclized mitochondria-penetrating peptides

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02075F, CommunicationGemin Fang, Xiangming Meng, Qian-Qian Yang, Liang-Jing Zhu, Tongkuai Xi, Meng Wu, Hanying Zhu, Xiao-Xu Chen, Chuan Sun, Changzhi Xu A series of cyclic Arg-rich mitochondrial penetrating peptides were prepared with variation at macrocycle size and the chirality of Arg residues. A cyclic heptapeptide was demonstrated as an efficient mitochondria-specific... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 23, 2019 Category: Molecular Biology Authors: Gemin Fang Source Type: research