Track density imaging: A reliable method to assess white matter changes in Progressive Supranuclear Palsy with predominant parkinsonism

Track density imaging (TDI) has been proven to be a useful approach able to investigate white matter (WM) anatomical integrity in several neurodegenerative conditions, such as Parkinson's disease (PD) and classical phenotype of Progressive Supranuclear Palsy (PSP) also known as Richardson's syndrome (RS). To the best of our knowledge, no studies have assessed WM changes in PSP-predominant parkinsonism (PSP –P) patients by using a TDI approach, and no studies have explored the potential role of these changes in discriminating patients with PSP-P from those with PSP-RS and PD.

Source: Parkinsonism and Related Disorders - October 21, 2019 Category: Neurology Authors: Salvatore Nigro, Gaetano Barbagallo, Maria Giovanna Bianco, Maurizio Morelli, Gennarina Arabia, Andrea Quattrone, Sara Gasparini, Giuseppe Lucio Cascini, Aldo Quattrone Source Type: research