Pentraxin 3: a novel target in the obesity –inflammation cascade

This editorial refers to ‘Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity’, by F. Bonacinaet al., pp. 1861 –1872.
Source: Cardiovascular Research - Category: Cardiology Source Type: research

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ConclusionsThis study provides important evidence for planners, urban designers, and policy makers on the significance of built environment, in general, and street network configuration, in particular, within home- and school-environments. One rule of thumb would be to design a well-connected street network with relatively denser connections and reduced direction changes within the neighbourhood – not only within a couple of blocks of homes and schools but also within their larger fabric (800–1600 mt buffers).
Source: Journal of Transport and Health - Category: Occupational Health Source Type: research
We investigated whether family income gradients in obesity, overweight, and adiposity persist at geographic-level deprivation quintiles using a nationally representative cohort of UK adolescents. Data from 11,714 eligible adolescents from the sixth sweep o...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
ABSTRACT Objective: To describe a case of a male adolescent with symptomatic idiopathic intracranial hypertension (IIH) associated with obesity treated with bariatric surgery. Case description: A 16-year-and-6-month-old severely obese boy [weight: 133.6 kg; height: 1.74 m (Z score: +0.14); BMI: 44.1 kg/m2 (Z score: +4.4)], Tanner pubertal stage 5, presented biparietal, high-intensity, and pulsatile headaches, about five times per week, associated with nocturnal awakenings, and partial improvement with common analgesics, for three months. Ophthalmologic evaluation evidenced bilateral papilledema. Cranial computed tomography...
Source: Revista Paulista de Pediatria - Category: Pediatrics Source Type: research
Publication date: Available online 16 January 2020Source: Canadian Journal of CardiologyAuthor(s): Maxime Boidin, Nicolas Handfield, Paula A.B. Ribeiro, Laurence Desjardins-Crépeau, Christine Gagnon, Gabriel Lapierre, Vincent Gremeaux, Julie Lalongé, Anil Nigam, Martin Juneau, Mathieu Gayda, Louis BhererAbstractBackgroundObesity is associated with an accelerate cognitive decline. However, aerobic fitness (peak V˙O2) has a protective effect on cognition in older adults but no study investigated this effect in obese individuals. The present study aimed at 1) comparing cognitive function in lower-fit (LoFit) an...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ConclusionSubstantial agreement exists among experts regarding many strong recommendations for the improvement of practice concerning the use of muscle relaxants and reversal agents during anaesthesia. In particular, the French Society of Anaesthesia and Intensive Care (SFAR) recommends the use of a device to monitor neuromuscular blockade throughout anaesthesia.
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
In conclusion, polyphenol compounds and their principal metabolites may contribute to counteracting human obesity via promoting WAT browning.
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 16 January 2020Source: Saudi Journal of Biological SciencesAuthor(s): Salina Y. SaddickAbstractThe pathophysiology of polycystic ovary syndrome (PCOS) is confusing until today as it is a multifactorial endocrine disorder. It is presented with altered gonadotropin levels, bulky multi-follicular ovaries, infertility, and obesity. This complex pathophysiology is linked with insulin resistance and hyperandrogenism. Hyperandrogenemia significantly contributes towards cosmetic anomalies including hirsutism, acne, and alopecia in the PCOS women. The preexisting insulin resistance in women with P...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
ConclusionsThe findings of this study indicate high prevalence of metabolic risk factors among study population. This study with a large sample size would contribute to establishment of efficient interventions and programs aimed at reducing the prevalence of MetS by health staff, supervisors and policymakers.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
We describe how to achieve the dietary prescription for energy and protein using breastmilk, formulas, food, and dietary supplements, which can be incorporated into everyday practice. Statements with a low grade of evidence, or based on opinion, must be considered and adapted for the individual patient by the treating physician and dietitian according to their clin ical judgment. Research recommendations have been suggested. The CPRs will be regularly audited and updated by the PRNT.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
BACKGROUND: Perceived neighborhood characteristics, including satisfaction with one's neighborhood as a place to live, are associated with lower obesity rates and more favorable cardiovascular risk factor profiles. Yet, few studies have evaluated whether c...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Pedestrians and Bicycles Source Type: news
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