Sirenomelia: Study of Three Cases

AbstractSirenomelia is a rare congenital anomaly which is an extreme example of caudal regression syndrome characterized by lower limb fusion, sacral and pelvic bony anomalies with abnormalities in other organ systems, commonly affecting the gastrointestinal and the urogenital systems (Kanagagiri et al. JMSCR 5(7),2017). It is a sporadic occurence with no increased risk in subsequent pregnancies. The syndrome of caudal regression is thought to be the result of injury to the caudal mesoderm early in gestation (Mirzapur et al. Glob J Reprod Med 3(5):555624,2018). Prenatal sonographic findings of sirenomelia (or mermaid fetus) were retrospectively reviewed in three proven cases.
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research