The necessity of IIb dissection in T1 –T2N0M0 oral squamous cell carcinoma: protocol for a randomized controlled trial

DiscussionCurrently, there are no randomized controlled trials with large sample sizes on the necessity of IIB dissection in T1 –T2N0M0 OSCC. We designed this noninferiority RCT that combines survival rate and HRQoL to assess the feasibility of IIb neck dissection. The result of this trial may guide clinical practice and change the criteria of how early-stage oral cancer is managed. The balance between survival and HRQoL i n this trial is based on early-stage breast cancer treatment and may provide new ideas for other malignancies.Trial registrationChinese Clinical Trial Registry,ChiCTR1800019128. Registered on 26 October 2018.
Source: Trials - Category: Research Source Type: clinical trials