PM2.5 disturbs the balance of Th17/Treg cells by targeting Got1 and HIF-1 α in an asthma model

Exposure to PM2.5 or PAHs was associated with asthma severity, which disturbed the Th17/Treg balance and aggravated asthma through AhR –HIF-1α and AhR–Got1 axes.

Source: Journal of Allergy and Clinical Immunology - October 20, 2019 Category: Allergy & Immunology Authors: Licheng Sun, Jinrong Fu, Sheng-Hao Lin, Jin-Lyu Sun, Li Xia, Ching-Hsiung Lin, Lijuan Liu, Caiyan Zhang, Lan Yang, Ping Xue, Xiang Wang, Saihua Huang, Xiao Han, Hua-Ling Chen, Ming-Shyan Huang, Xiaobo Zhang, Shau-Ku Huang, Yufeng Zhou Source Type: research