Efficacy, safety and immunogenicity of a pneumococcal protein-based vaccine co-administered with 13-valent pneumococcal conjugate vaccine against acute otitis media in young children: A phase IIb randomized study.

CONCLUSIONS: The dPly/PhtD vaccine was immunogenic and well tolerated, however, incremental efficacy in preventing AAP-AOM over PCV13 was not demonstrated.
CLINICAL TRIALS REGISTRATION: NCT01545375 (www.clinicaltrials.gov).
PMID: 31629570 [PubMed - as supplied by publisher]

Source: Vaccine - October 15, 2019 Category: Allergy & Immunology Authors: Hammitt LL, Campbell JC, Borys D, Weatherholtz RC, Reid R, Goklish N, Moulton LH, Traskine M, Song Y, Swinnen K, Santosham M, O'Brien KL Tags: Vaccine Source Type: research