Oxone®-Promoted One-Pot Synthesis of 1-Aryl-4-(organylselanyl)-1H-pyrazoles

We describe herein an efficient protocol for the one-pot synthesis of 4-organylselanylpyrazoles by direct cyclocondensation and C-H bond selenylation reactions starting from hydrazines, 1,3-diketones and diorganyl diselenides promoted by Oxone ®. The products were obtained through a metal catalyst free methodology, under mild conditions, in short reaction times and moderate to excellent yields.
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research