Persistent fever due to acute pancreatic graft  rejection

A 36-year-old female recipient of simultaneous pancreas-kidney transplantation 2 months previously was admitted to the emergency room because of a fever of unknown origin. Physical examination was unremarkable. Klebsiella pneumoniae was isolated in urine culture and treated with ceftriaxone according to antibiogram. High-grade fever persisted despite the increase in antibiotic spectrum with meropenem. Blood cultures were negative (including mycobacteria), as were quantiferon, cytomegalovirus, BK virus, Epstein –Barr virus polymerase chain reaction, and Toxoplasma gondii serologies.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research