Cell transfer ‐based immunotherapies in cancer: A review

In cell transfer therapy (CTT), immune cells such as innate immune ‐derived natural killer cells and dendritic cells as well as acquired immune‐related T lymphocytes such as tumor‐infiltrating lymphocytes and cytokine‐activated or genetically modified peripheral blood T cells are used in the management of cancer. These therapies are increasingly becoming th e most used treatment modality in cancer after tumor resection, chemotherapy, and radiotherapy. In adoptive cell transfer, the lymphocytes isolated from either a donor or the patient are modified ex vivo and reinfused to target malignant cells. Transferring in vitro‐manipulated immune cells produc es a continuous antitumor immune response. In this review, we evaluate the recent advances in CTT for the management of various malignancies.
Source: IUBMB Life - Category: Research Authors: Tags: CRITICAL REVIEW Source Type: research

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Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
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Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
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Source: European Urology - Category: Urology & Nephrology Source Type: research
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research
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Source: Der Chirurg - Category: Surgery Authors: Tags: Chirurg Source Type: research
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Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
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