Acetaminophen combined with tramadol is more effective than acetaminophen or tramadol to reduce neuropathic root pain: an experimental study with application of nucleus pulposus in a rat model

ConclusionCombined administration of acetaminophen and tramadol maintained in the pain threshold in the rat NP model. These findings suggest that the combination of acetaminophen and tramadol might be a potential therapeutic modality for patients with lumbar disc herniation.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.

http://link.springer.com/10.1007/s00586-019-06190-z

Source: European Spine Journal - October 20, 2019 Category: Orthopaedics Source Type: research