Physical function and health-related quality of life in the convalescent phase in surgically treated patients with malignant pleural mesothelioma

This study aimed to assess physical function and HRQOL of MPM patients following pleurectomy/decortication (P/D) in the convalescent phase.MethodsThe study included 16 male MPM patients who underwent P/D between September 2014 and August 2016. Physical function was assessed based on handgrip and knee extensor strengths, the six-minute walk distance (6MWD), and pulmonary function, including forced vital capacity (FVC) and forced expiratory volume in one second (FEV1). HRQOL was assessed using the Medical Outcome Study 36-item Short Form Health Survey (SF-36). The assessment was performed preoperatively, postoperatively, and 1-year after surgery.ResultsThe 6MWD, FVC, and FEV1 values 1-year postoperatively improved significantly compared with baseline (P 
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research

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Conclusions This study demonstrated that adding bevacizumab to standard chemotherapy in patients with advanced MPM had no negative impact on HRQoL. A significant improvement in the peripheral neuropathy and pain HRQoL dimensions was even observed. PMID: 31175096 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
This article represents his opinions. The Environmental Protection Agency would like you to think it is taking an “unprecedented” stand against the hazards of asbestos, the mineral that kills nearly 40,000 Americans each year from mesothelioma, lung cancer and other asbestos-related diseases. It is not. In fact, on June 1, the EPA announced a significant new use rule (SNUR) that will allow companies to manufacture, import and process new asbestos-containing products after it evaluates their potential health dangers. The standards to evaluate those health risks, which are included in a nearly 1,500-page docume...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
This article is protected by copyright. All rights reserved. PMID: 30004629 [PubMed - as supplied by publisher]
Source: Clinical Lung Cancer - Category: Cancer & Oncology Authors: Tags: Clin Respir J Source Type: research
If you have been diagnosed with mesothelioma, you’re likely seeking information and resources to learn more about the disease. A free one-hour mesothelioma teleconference is a great place to start. CancerCare recently hosted the “Advancements in the Treatment of Mesothelioma” workshop. The session featured five mesothelioma experts, including Dr. Hedy Kindler, director of the mesothelioma program at the University of Chicago Comprehensive Cancer Center. The Mesothelioma Applied Research Foundation co-sponsored the teleconference, which is available online for free. All mesothelioma patients can benefit f...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
AbstractIntroductionMalignant pleural mesothelioma (MPM) is a rare cancer that affects the thin cell wall lining of internal organs and structures. Studies have shown that patients with lung cancer have decreased pulmonary function and exercise capacity after pneumonectomy. However, to date, physical function and health-related quality of life (HRQOL) in surgically treated MPM patients have not been evaluated in detail. The aim of this study was to assess physical function and HRQOL of MPM patients following pleurectomy/decortication (P/D).MethodsThe subjects were 22 MPM patients (20 men and 2 women) who completed P/D betw...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
TheCochrane Priority Reviews List is a ‘living’ record of Cochrane’s attempt to identify reviews that are of greatest importance to our stakeholders and are likely to impact significantly on health outcomes worldwide. The list is updated in real time as reviews are published and new titles added.Some of the titles on the list are open to new authors. If you are interested in one of these open titles please contact the relevantCochrane Review Group before submitting a review proposal:Continuous glucose monitoring systems for monitoring CF-related diabetes(Cochrane Cystic Fibrosis&Genetic Disorders)&mid...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
Thoracic surgeon Dr. Jacques Fontaine at the Moffitt Cancer Center in Tampa believes there is a well-marked path to improving the stubbornly high mortality rate for lung cancer. The breast cancer community already has blazed the trail. "Some of the things that really changed the face of breast cancer 20 years ago, are now taking hold with lung cancer," Fontaine told Asbestos.com. "Hopefully, we're going to start seeing more progress." November is Lung Cancer Awareness Month, a time to focus on what needs to be done, what should be done better, and what breast cancer has taught everyone. While progr...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: Research & Clinical Trials Source Type: news
Conclusions The initial safety profile of LY2090314 was established. MTD LY dose with pemetrexed/carboplatin is 40 mg IV every 3 weeks plus ranitidine. Efficacy of LY plus pemetrexed/carboplatin requires confirmation in randomized trials.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research
Conclusions Advanced stages at presentation reflect the palliative pattern of treatment. Hypo-fractionated radiotherapy for lung and pleura malignancies as a palliative measure is the current practice. Implementation of early palliative care should be considered for metastatic patients.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
We all appreciate the elegance of simple solutions to complex problems. But we know too that simplicity can often masquerade as truth, hiding a more nuanced reality. Such is the case with inflammation, where pseudoscience, exaggerated claims, false promises, and dangerous oversimplification have dominated for too long. Here is a typical missive: "Inflammation controls our lives. Have you or a loved one dealt with pain, obesity, ADD/ADHD, peripheral neuropathy, diabetes, heart disease, stroke, migraines, thyroid issues, dental issues, or cancer? If you answered yes to any of these disorders you are dealing with inflam...
Source: Science - The Huffington Post - Category: Science Source Type: news
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