GSE121893 Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing

Contributors : Li Wang ; Peng Yu ; Zheng Li ; Zongna RenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe studied the cell compositon of two types of human heart disease (coronary atherosclerotic heart disease and dilated cardiomyopathy) by single-cell sequencing. Distinct subgroups of cardiac muscle, fibroblast cell and endothelial cell were detected. We generated a cell-cell interaction network using specific expressed ligands and receptors of cells. And we also observed the change of interaction and cell transformation with age.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research