Cortisol, oxytocin, and quality of life in major depressive disorder

ConclusionsThis study provides novel evidence linking neuroendocrine pathways to particular domains of QoL in MDD. The results indicate that activity of the hypothalamic –pituitary–adrenal axis is linked to poor psychological QoL, and that oxytocin is important to social QoL, independently of severity of psychopathology. Biopsychosocial approaches to QoL associated with mental health conditions may lead to greater understanding of the underlying mechanisms and t o improved, tailored interventions.
Source: Quality of Life Research - Category: Health Management Source Type: research