AAA 11. Outcomes After Aortic Aneurysm Repair in Patients With History of Cancer With a Nationwide Data Set Analysis

Synchronous cancer in patients with abdominal aortic aneurysm (AAA) increases their morbidity and mortality after AAA repair. However, little is known about the history of cancer in AAA patients and its impact on mortality after AAA repair. We analyzed the incidence and type of cancer history in patients who underwent AAA repair and difference in short- and long-term mortality.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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A 75-year-old morbidly obese man presented with increasing diameter of a known abdominal aortic aneurysm (AAA) and right common iliac artery aneurysm. He was diagnosed with these aneurysms at the age of 69  years while undergoing computed tomography for evaluation of pancreatic cancer. At the time of diagnosis, the AAA diameter was 3.9 cm. His past medical history was significant for hypertension and hyperlipidemia. He was observed with serial aortoiliac duplex ultrasound scans. By November 2018 (6  years after the original diagnosis), the AAA diameter increased to 6.3 cm and the right common iliac arte...
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Vascular images Source Type: research
CONCLUSIONS: This retrospective, single-center study shows that, within a population of similar clinical and anatomic characteristics, treatment of AAA with EVAR or HALS does not result in significant differences in early morbidity and mortality. EVAR presents significantly shorter hospital and intensive care unit length of stay, whereas HALS presents a lower aneurysm-related reintervention rate and lower perioperative cost. The strict patient selection in this trial, as is generally the case with AAA treatment, is likely the key to success for both of these techniques. PMID: 30718111 [PubMed - as supplied by publisher]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Vasc Surg Source Type: research
This study examined the hypothesis that EVAR leads to an increased risk of abdominal cancer within the radiation field compared with open AAA repair.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
None of the predictive models for venous thromboembolism (VTE) prophylaxis have been designed for and validated in patients undergoing cardiothoracic and vascular surgery. The presence of one or more risk factors [age over 70 years old, transfusion of more than 4 U of red blood cells/fresh frozen plasma/cryoprecipitate, mechanical ventilation lasting more than 24 h, postoperative complication (e.g. acute kidney injury, infection/sepsis, neurological complication)] should place the cardiac population at high risk for VTE. In this context, we suggest the use of pharmacological prophylaxis as soon as satisfactory haemosta...
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Guidelines Source Type: research
Question: An 82-year-old asymptomatic man presented with an incidental finding of liver lesion on a computed tomography (CT) angiogram performed for infrarenal abdominal aortic aneurysm repair surveillance. He had a history of bladder cancer 7 years prior, with no evidence of disease since the end of the treatment. He did not have history of  liver disease or immunosuppression. At presentation, his laboratory examinations were normal. He underwent abdominal magnetic resonance imaging (MRI) that showed a 3.5 × 3.0-cm liver mass in segment II/IVA; the mass was T2-weighted images mildly hyperintense (Figure A,...
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Clinical Challenges and Images in GI Source Type: research
None of the predictive models for venous thromboembolism (VTE) prophylaxis have been designed for and validated in patients undergoing cardiothoracic and vascular surgery. The presence of one or more risk factors [age over 70 years old, transfusion of more than 4 U of red blood cells/fresh frozen plasma/cryoprecipitate, mechanical ventilation lasting more than 24 h, postoperative complication (e.g. acute kidney injury, infection/sepsis, neurological complication)] should place the cardiac population at high risk for VTE. In this context, we suggest the use of pharmacological prophylaxis as soon as satisfactory haemosta...
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Guidelines Source Type: research
This study complements the recently published update of its contemporary trial in the United Kingdom, Endovascular Aneurysm Repair (EVAR) trial 1.1 The main contribution of the DREAM update, at least the sixteenth in the series (PubMed search, June 7, 2017; keywords Blankenstei jn and DREAM), is the observation that unlike in the EVAR 1 experience, participants randomized to EVAR in DREAM did not experience increased late all-cause mortality or cancer incidence compared with those treated with open surgical repair.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Editorial Source Type: research
ConclusionsIn this patient,C. septicum was thought to have entered his blood through a gastrointestinal tumor, infected the aorta, and spread to his kidneys. However, we were uncertain whether there was an associated malignancy.A literature review ofC. septicum-related aneurysms revealed the following: 6-month mortality, 79.5%; periaortic gas present in 92.6% of cases; no standard operative procedure and no guidelines for antimicrobial administration established; andC. septicum was associated with cancer in 82.5% of cases.Thus, we advocate for early diagnosis via the identification of periaortic gas, as an aortic aneurysm ...
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
In this study, we test the effect of screening and subsequent intervention for abdominal aortic aneurysm, peripheral arterial disease, and hypertension combined. Methods In this randomised controlled trial, we randomly allocated (1:1) all men aged 65–74 years living in the Central Denmark Region to screening for abdominal aortic aneurysm, peripheral arterial disease, and hypertension, or to no screening. We based allocation on computer-generated random numbers from 1 to 100 in blocks of 1067 to 4392, stratified by 19 municipalities. Only the non-screening group and the investigator assessing outcomes were masked. We ...
Source: The Lancet - Category: General Medicine Source Type: research
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