CAR 12. Emergent Carotid Revascularization for Acute Stroke Therapy: A Role for Open Surgery and Catheter-Based Therapy Based on Brain Imaging

Recent studies have expanded the window for the use of systemic and catheter-directed thrombolysis and mechanical thrombectomy for acute stroke management. The purpose of this review was to evaluate the impact that contemporary cerebral imaging has on the indications for emergent cervical carotid revascularization.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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Authors: Yoshida K, Miyamoto S, SMART-K Study Group Abstract With recent advances in medical treatments for carotid artery stenosis (CS), indications for carotid surgery should be more carefully considered for asymptomatic CS (ACS). Accurate stratification of ACS should be based on the risk of cerebral infarction, and subgroups of patients more likely to benefit from surgical treatment should be differentiated. Magnetic resonance imaging (MRI) offers a non-invasive, accurate modality for characterizing carotid plaque. Intraplaque hemorrhage (IPH) seems the most promising feature of vulnerable plaque detectable by M...
Source: Neurologia Medico-Chirurgica - Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research
Conditions:   Stroke, Ischemic;   Self Efficacy Intervention:   Behavioral: The effect of education and telephone follow ups based on the Chronic Care Model on self-management, quality of life and patient satisfaction in patients with ischemic stroke Sponsor:   Akdeniz University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsThe bilateral rubral branches were differentially involved in the chronic capsular and pontine stroke, and the impairment severity of each rubral branch was dependent on lesion locations. The integrity of the rubral branches is related to motor impairment in both the chronic capsular and pontine stroke.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Conclusionscortical gamma synchrony related to auditory entrainment can be reliably measured in stroke patients. Gamma synchrony is strongly associated with the clinical outcome of stroke survivors undergoing rehabilitation.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Our previous studies showed that propane-2-sulfonic acid octadec-9-enyl-amide (N15), a novel peroxisome proliferator-activated receptors α and γ (PPARα/γ) dual agonist, protected against ischaemia-induced acute brain damage in mice and improved cognitive ability in the chronic phase of ischaemic stroke. It is well known that hippocampal neurogenesis is closely related to cognitive function. In the present study, we investigated the effect of N15 on hippocampal neurogenesis and neuroplasticity in a middle cerebral artery occlusion (MCAO) rat model. The middle cerebral artery of rats was blocked for 2...
Source: NeuroReport - Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
Objective: We aimed to identify brain changes associated with preserved cognitive function in patients with chronic brainstem stroke. Methods: Twelve patients with chronic brainstem stroke and 24 age-matched healthy controls were included in this retrospective study. All participants underwent T1-weighted, diffusion tensor, and resting-state functional MRI. Gray matter density, fractional anisotropy, and mean diffusivity maps from diffusion tensor imaging and seven cognition-related independent component maps from resting-state functional MRI were used to identify differences in brain volume, structural connectivity, ...
Source: NeuroReport - Category: Neurology Tags: Clinical Neuroscience Source Type: research
The Dutch philosopher and artist believes we should change our relationship to animals. This involves recognising that they talk to us – and granting them proper rightsFagan the horse is enormous, nervy and then, suddenly, inexplicably calm when Eva Meijer strokes his neck and whispers in his twitching ears. Meijer, a Dutch philosopher, novelist, visual artist and singer-songwriter, is visiting the splendidly acronymed Faith (For Animals In Trouble, there ’s Hope) animal rescue centre in Norfolk.Our photographer is hoping to obtain a portrait of Meijer talking to the animals, Dr Dolittle-style, for this intervi...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Animal behaviour Biology Science Source Type: news
Abstract Heat stroke is a symptom of hyperthermia with a temperature of more than 40 °C, which usually leads to all kinds of physical discomfort and even death. It is necessary to study the mechanism of action of heat stroke on cells or organelles (such as cytotoxicity of heat) and the processes of cells or organelles during heat stroke. Recent studies have shown that there is a certain correlation between heat stroke and lysosome acidity. In order to clarify their relationship, Lyso-NIR-pH, a photostable Si-rhodamine-based near-infrared fluorescent probe, was developed for sensing pH changes in lysosomes du...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
(University of Pennsylvania School of Medicine) Taller people have an increased risk of developing atrial fibrillation (AFib), an irregular and often rapid heartbeat that can lead to stroke, heart failure and other complications, according to a new Penn Medicine study. The research, which reveals a strong link between the genetic variants associated with height and one's risk for AFib, is the among the first to demonstrate that height may be a causal -- not correlated -- risk factor for AFib.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01679A, PaperKyu Shik Eom, Yijae Lee, Hye Won Seo, Ji Yoon Kang, Joon S. Shim, Soo Hyun Lee An excessive cholesterol level can lead to cardiovascular diseases, such as stroke, hypertension, and myocardial infarction. A non-invasive, painless method of determining the cholesterol in the blood would improve the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
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