LEV 1. Endovenectomy of the Common Femoral Vein as Last Option in Severe Post-thrombotic Syndrome

The common femoral vein (CFV) and iliac veins compose the common channel for venous drainage of the lower extremity. Occlusive venous thrombosis of the CFV and iliac veins is associated with severe post-thrombotic syndrome and in some cases with nonhealing vein ulcers. After percutaneous intervention, relative obstruction of the CFV can persist, leading to incomplete drainage of the femoral and profunda femoris venous systems, thereby mitigating the benefit of iliac vein recanalization and risking rethrombosis; associated restenosis intrastent could occur, resulting in a great challenge for endovascular management.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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Authors: PMID: 31743216 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Tags: Anesth Analg Source Type: research
AbstractThere is still a debate about the safety and efficacy of an aspirin free strategy after percutaneous coronary intervention (PCI). Hence, we performed a meta-analysis comparing aspirin free strategy to dual antiplatlets therapy (DAPT). Randomized trials (RCTs) comparing aspirin free strategy to DAPT in patients who received PCI were included. The primary outcome of interest was bleeding, defined per the Bleeding Academic Research Consortium (BARC). Secondary outcomes included major adverse cardiovascular and cerebrovascular events (MACE); defined as all-cause mortality, myocardial infarction or stroke, the individua...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
ConclusionsLow molecular weight heparin may be a safer option in patients with cirrhosis treated for acute venous thromboembolism, but future studies should confirm these findings.
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research
WEDNESDAY, Nov. 20, 2019 -- There are associations between rheumatoid arthritis (RA) and multiple comorbidities before and after diagnosis, with inflammatory bowel disease, type 1 diabetes, and venous thromboembolism (VTE) occurring more often...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
The number and complexity of procedures performed by gastroenterologists are increasing in the United States.1,2 In addition, the number and complexity of antithrombotic agents are growing.3 These concurrent trends may lead to confusion among providers on the  appropriate management of these drugs during endoscopy. The skilled clinician must balance the risks of thrombosis, including myocardial infarction and stroke, against the risks of procedure-related hemorrhage, which can be potentially fatal.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
ConclusionAMI as a result of penetrating trauma is rare, but can occur secondary to an acute thrombus, even in the absence of a direct cardiac injury. MI should be a consideration in patients with penetrating trauma to the chest, regardless of the intensity of the trauma. At minimum, a 12-lead electrocardiogram (ECG) and a baseline troponin should be obtained at initial evaluation and post-operatively, if surgically managed. If ECG demonstrates findings concerning for MI, it should be followed with an echocardiogram and/or cardiac angiogram to further help guide management, with an early cardiology consultation.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Authors: Borgel D, Bianchini E, Lasne D, Pascreau T, Saller F Abstract Deep vein thrombosis is a common disease associated with a variety of complications including post-thrombotic syndrome as a late complication. It is now clear that in addition to classical deep vein thrombosis triggers such as blood flow disturbance, hypercoagulability, and vessel wall changes, inflammation has a key role in the pathophysiology of deep vein thrombosis, and there is a close relationship between inflammation and coagulation. As attested by changes in several plasma biomarkers, inflammation may have a significant role in the develo...
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research
Authors: Nishikawa T, Oka T, Shioyama W, Kashimoto K, Yasui T, Oboshi M, Kamada R, Fujita M Abstract Venous thromboembolism occurs in prothrombotic states, such as malignancy. To prevent fatal pulmonary thromboembolism, an indwelling inferior vena cava (IVC) filter is considered in addition to anticoagulation therapy. We herein report a case of fracture of a retrievable IVC filter in a malignant lymphoma patient. One of the filter arms was fractured and fixed to the IVC wall after one year. Since dislocation of the fractured arm was assessed correctly using three-dimensional computed tomography, we were able to ret...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conclusion: Our study indicates that the application of chemical additives in cell lysis can improve the solubility of reteplase. Further studies are still required to understand the exact mechanism of chemical additives as a chemical chaperone during cell lysis. PMID: 31737582 [PubMed]
Source: Biomed Res - Category: Research Authors: Tags: Adv Biomed Res Source Type: research
AbstractPurpose of ReviewAtrial fibrillation (AF) is the most common arrhythmia in adults. The number of patients with AF is anticipated to increase annually, mainly due to the aging population alongside improved arrhythmia detection. AF is associated with a significantly elevated risk of hospitalization, stroke, thromboembolism, heart failure, and all-cause mortality. Echocardiography is one of the key components of routine assessment and management of AF. Therefore, the aim of this review is to briefly summarize current knowledge on “novel” echocardiographic parameters that may be of value in the management o...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
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