MISC 15. Trends in Survival of Women Younger and Older Than 55  Years After Major Vascular Intervention: A Sex and Age Comparison

The literature has shown a correlation between estrogen production and vascular protection (anti-inflammatory and vasoprotective effects). Therefore, as estrogen production decreases after menopause, there is an increase in cardiovascular risk. The aim of this study was to evaluate survival of women younger and older than 55  years after major vascular intervention and to compare it with that of age-matched men.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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Abstract The Editor-in-Chief has retracted this article [1] because an investigation by Keio University has concluded that there are inaccuracies in the data reported. PMID: 31730223 [PubMed - in process]
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
ConclusionPLO has a significant impact on pain, mental state, quality of life, and capacity to work. However, the long-term prognosis is promising. The severe mental distress is presumably related to several contributing factors in life such as physical integrity and independence, family life, employment, and financial security.Key Points• PLO has a strong impact on quality of life and can lead to severe mental distress.• At onset of symptoms, patients with PLO are in very poor mental and physical condition; however, the long-term outcome after inpatient rehabilitation seems to be good.• Most patients do not...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
ConclusionMenopausal symptoms improved significantly in both groups (MHT and CR), while serum metabolic parameters and body weight did not change in MHT- or CR-treated women.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Abstract Leonurus cardiaca L. (motherwort) is a perennial herb, native to Asia and southeastern Europe, with widespread global occurrence in present days. The plant was historically used as cardiotonic and for treating gynaecological afflictions (such as amenorrhea, dysmenorrhea, menopausal anxiety, or postpartum depression). Although its use in oriental and occidental medicine is relatively well documented, the recent progress registered raises the need for an update of the Medicines Agency assessment report on Leonurus cardiaca L., herba (2010). The current study presents the progress made within the 2010-2018 t...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Introduction: Clinicopathologic and prognostic significance of body mass index (BMI) in breast cancer (BC) patients remained conflicting. We aimed to investigate and modify the impact of BMI on clinicopathological significance and survival in western Chinese BC patients. Materials and Methods: 8,394 female BC patients from Western China Clinical Cooperation Group (WCCCG) between 2005 and 2015 were identified. Multivariable logistic regression and Cox proportion hazard regressions were used to examine the difference of clinicopathologic and survival characteristics between BMI categories. Results...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Publication date: Available online 15 November 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Marco Mezzullo, Carla Pelusi, Alessia Fazzini, Andrea Repaci, Guido Di Dalmazi, Alessandra Gambineri, Uberto Pagotto, Flaminia FanelliAbstractMeasuring some sex and precursor steroids is still challenging even by liquid chromatography – tandem mass spectrometry (LC-MS/MS), and few normal values are available. We developed a LC-MS/MS method for estradiol, estrone, dihydrotestosterone and 17-hydroxypregnenolone measurement, compared it with direct immunoassays, and generated sex, age, menopausa...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Authors: Lega IC, Lipscombe LL Abstract Obesity and diabetes have both been associated with an increased risk of cancer. In the face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer rates. Factors such as hyperinsulinemia, chronic inflammation, anti-hyperglycemic medications and shared risk factors have all been identified as potential mechanisms underlying the relationship. The most common obesity- and diabetes-related cancers are endometrial, colorectal and post menopausal breast cancers. In this review, we summarize the existing evidence that describes the complex relations...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
(The North American Menopause Society (NAMS)) For some women, sex becomes less satisfying with age, with a pronounced decline during perimenopause. A new study indicates that sexual dysfunction increases by nearly 30% during perimenopause, and vaginal dryness most often has the greatest effect on desire, arousal, lubrication, and overall satisfaction. Study results were published this week in Menopause, the journal of The North American Menopause Society (NAMS).
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
In conclusion, leanness and exercise do not necessarily protect from OVX-induced weight gain. Exercise prevented weight gain in obese rats, but loss of SPA was the greatest contributor to post-OVX weight gain. Thus, understanding the mechanisms resulting in reduction in SPA after ovarian hormone loss is critical in the prevention of menopause-associated metabolic dysfunction.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research
ConclusionIn general, POP-Q C-D was longer than the cervical length measured by MRI. Deep analysis found that when uterine prolapse is combined with larger anterior vaginal wall prolapse, the difference between ECL and MCL is greater; when uterine prolapse with larger posterior vaginal wall prolapse, the difference between ECL and MCL is smaller.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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